Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867931 | 1.00 | TP53 (0.46) | TP53NPY5RSMN1; SMN2TSHRKMT2A | |
| SCHEMBL6878437 | 0.93 | NPY5R (0.43) | TP53NPY5RSMN1; SMN2MCHR1RAB9A | |
| SCHEMBL6878430 | 0.93 | NPY5R (0.43) | TP53NPY5RSMN1; SMN2MCHR1RAB9A | |
| SCHEMBL6456897 | 0.93 | MEN1 (0.42) | TP53NPY5RSMN1; SMN2KMT2AMCHR1 | |
| SCHEMBL6456892 | 0.93 | MEN1 (0.42) | TP53NPY5RSMN1; SMN2KMT2AMCHR1 | |
| Hydrochloric Acid SCHEMBL6459011 | 0.92 | MEN1 (0.41) | TP53NPY5RSMN1; SMN2KMT2AMCHR1 | |
| Hydrochloric Acid SCHEMBL6459006 | 0.92 | MEN1 (0.41) | TP53NPY5RSMN1; SMN2KMT2AMCHR1 | |
| SCHEMBL6868236 | 0.90 | NPY5R (0.43) | NPY5RSMN1; SMN2MCHR1LMNAADRA2A | |
| SCHEMBL6868239 | 0.90 | NPY5R (0.43) | NPY5RSMN1; SMN2MCHR1LMNAADRA2A | |
| SCHEMBL6867311 | 0.89 | KDM4E (0.43) | TP53NPY5RSMN1; SMN2KMT2AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |