Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 12/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 7/20 | 0.54 |
| ▸ | HTR2B | P41595 | 5/20 | 0.54 |
| ▸ | HRH1 | P35367 | 4/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6868089 | 1.00 | MCHR1 (0.54) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL7047765 | 0.90 | MCHR1 (0.56) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL7047759 | 0.90 | MCHR1 (0.56) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6868729 | 0.89 | MCHR1 (0.58) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6868895 | 0.89 | MCHR1 (0.58) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6868889 | 0.89 | MCHR1 (0.58) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6875374 | 0.89 | MCHR1 (0.54) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6878008 | 0.89 | MCHR1 (0.54) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6878002 | 0.89 | MCHR1 (0.54) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6875373 | 0.89 | MCHR1 (0.54) | MCHR1ADRA2AHTR2BHRH1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |