⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28121813 | 0.83 | GGPS1 (0.31) | — | |
| SCHEMBL28121797 | 0.80 | TSHR (0.38) | — | |
| SCHEMBL21093333 | 0.74 | TDP1 (0.33) | — | |
| SCHEMBL11821293 | 0.72 | TSHR (0.36) | — | |
| SCHEMBL27943013 | 0.70 | MAPK1 (0.30) | — | |
| SCHEMBL25408854 | 0.69 | DNM1 (0.32) | — | |
| SCHEMBL7098358 | 0.67 | DNM1 (0.39) | — | |
| SCHEMBL7093917 | 0.67 | DNM1 (0.39) | — | |
| SCHEMBL6213345 | 0.66 | TDP1 (0.38) | — | |
| SCHEMBL12423880 | 0.65 | TSHR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938501-B1 | PROCESS FOR THE PURIFICATION OF HUMAN INTERLEUKIN-1 RECEPTOR ANTAGONIST FROM RECOMBINANT E. COLI | AVENTIS BULK S P A (IT) | 2004-07-28 | — | — | EP | claimed |
| EP-0938501-B1 | PROCESS FOR THE PURIFICATION OF HUMAN INTERLEUKIN-1 RECEPTOR ANTAGONIST FROM RECOMBINANT E. COLI | AVENTIS BULK S P A (IT) | 2004-07-28 | — | — | EP | disclosed |
| US-6573366-B1 | Loading the mixture onto a cationic exchange matrix and eluting with a buffered solution; applying onto an anionic exchange matrix, eluting and recovering | GRUPPO LEPETIT S.P.A. (IT) | 2003-06-03 | — | — | US | disclosed |