Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 10/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6868364 | 1.00 | MCHR1 (0.47) | MCHR1NPY5RADRA2AKDM4ELMNA | |
| SCHEMBL6874121 | 0.86 | MCHR1 (0.45) | MCHR1NPY5RADRA2AKDM4ELMNA | |
| SCHEMBL6874117 | 0.86 | MCHR1 (0.45) | MCHR1NPY5RADRA2AKDM4ELMNA | |
| SCHEMBL6466741 | 0.85 | MCHR1 (0.51) | MCHR1NPY5RADRA2AKDM4ELMNA | |
| SCHEMBL6466734 | 0.85 | MCHR1 (0.51) | MCHR1NPY5RADRA2AKDM4ELMNA | |
| SCHEMBL6874906 | 0.85 | MCHR1 (0.49) | MCHR1NPY5RADRA2AKDM4ELMNA | |
| SCHEMBL6874914 | 0.85 | MCHR1 (0.49) | MCHR1NPY5RADRA2AKDM4ELMNA | |
| SCHEMBL13796560 | 0.85 | MCHR1 (0.65) | MCHR1NPY5RADRA2A | |
| SCHEMBL6873607 | 0.85 | NPY5R (0.45) | MCHR1NPY5RADRA2AKDM4ELMNA | |
| SCHEMBL6873598 | 0.85 | NPY5R (0.45) | MCHR1NPY5RADRA2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |