Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 7/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6873598 | 1.00 | NPY5R (0.45) | NPY5RMCHR1ADRA2AAPPBCHE | |
| SCHEMBL6874665 | 0.93 | NPY5R (0.49) | NPY5RMCHR1ADRA2AAPPBCHE | |
| SCHEMBL6874670 | 0.93 | NPY5R (0.49) | NPY5RMCHR1ADRA2AAPPBCHE | |
| SCHEMBL6868105 | 0.91 | MCHR1 (0.48) | NPY5RMCHR1ADRA2AAPPBCHE | |
| SCHEMBL6873885 | 0.91 | MCHR1 (0.46) | NPY5RMCHR1ADRA2AAPPBCHE | |
| SCHEMBL6868098 | 0.91 | MCHR1 (0.48) | NPY5RMCHR1ADRA2AAPPBCHE | |
| SCHEMBL6873877 | 0.91 | MCHR1 (0.46) | NPY5RMCHR1ADRA2AAPPBCHE | |
| SCHEMBL6874567 | 0.90 | MCHR1 (0.54) | NPY5RMCHR1ADRA2AAPPBCHE | |
| SCHEMBL6874559 | 0.90 | MCHR1 (0.54) | NPY5RMCHR1ADRA2AAPPBCHE | |
| SCHEMBL6874117 | 0.90 | MCHR1 (0.45) | NPY5RMCHR1ADRA2ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |