Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.35 |
| ▸ | ITGAV | P06756 | 3/20 | 0.35 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.35 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.35 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688106 | 0.94 | KMT2A (0.41) | CTSAMEN1KMT2ACYP26A1HPGD | |
| SCHEMBL687910 | 0.92 | MEN1 (0.39) | CTSAMEN1KMT2AHPGDITGB3 | |
| SCHEMBL687271 | 0.91 | KMT2A (0.39) | CTSAMEN1KMT2ACYP26A1HPGD | |
| SCHEMBL688537 | 0.91 | KEAP1 (0.39) | MEN1KMT2ACYP26A1HPGDITGB3 | |
| SCHEMBL687592 | 0.91 | MEN1 (0.43) | CTSAMEN1KMT2ACYP26A1HPGD | |
| SCHEMBL688395 | 0.91 | MEN1 (0.37) | CTSAMEN1KMT2ACYP26A1HPGD | |
| SCHEMBL687858 | 0.91 | MEN1 (0.37) | CTSAMEN1KMT2ACYP26A1HPGD | |
| SCHEMBL686898 | 0.90 | MEN1 (0.39) | CTSAMEN1KMT2AHPGDITGB3 | |
| SCHEMBL687042 | 0.90 | MEN1 (0.37) | CTSAMEN1KMT2ACYP26A1HPGD | |
| SCHEMBL687372 | 0.90 | MEN1 (0.40) | CTSAMEN1KMT2ACYP26A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |