SCHEMBL68685

SCHEMBL68685

CCCCc1cc(Cl)c(O)cc1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.53
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
TDP1 Q9NUW8 3/20 0.46
HTT P42858 2/20 0.46
TSHR P16473 2/20 0.46
MAPT P10636 2/20 0.46
ALOX15 P16050 2/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
ALOX5 P09917 1/20 0.46
HPGD P15428 3/20 0.42
MAPK1 P28482 3/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
HMGCR P04035 1/20 0.40
HSD17B10 Q99714 2/20 0.39
KDM4E B2RXH2 3/20 0.39
ALDH1A1 P00352 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8763419 0.94 ALOX5 (0.53) TYRMEN1KMT2ATDP1HTT
SCHEMBL8764376 0.92 ALOX5 (0.56) TYRMEN1KMT2ATDP1HTT
SCHEMBL8763538 0.92 ALOX5 (0.56) TYRMEN1KMT2ATDP1HTT
SCHEMBL8763527 0.92 ALOX5 (0.56) TYRMEN1KMT2ATDP1HTT
SCHEMBL8763388 0.92 ALOX5 (0.56) TYRMEN1KMT2ATDP1HTT
SCHEMBL8764330 0.92 ALOX5 (0.56) TYRMEN1KMT2ATDP1HTT
SCHEMBL16736745 0.88 TYR (0.53) TYRMEN1KMT2ATDP1HTT
SCHEMBL8764455 0.88 HMGCR (0.52) TYRMEN1KMT2ATDP1HTT
SCHEMBL3382419 0.85 TYR (0.63) TYRMEN1KMT2ATDP1HTT
SCHEMBL16736915 0.85 TYR (0.50) TYRMEN1KMT2ATDP1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0623339-B1 Use of 4-,4- and 5-, or 4- and 6-substituted derivatives of resorcin in cosmetic or dermopharmaceutical compositions for depigmentation OREAL (FR) 1997-07-23 EP claimed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 TYR 134/4885MEN1 4831/4885KMT2A 1042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.