Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.46 |
| ▸ | HRH1 | P35367 | 3/20 | 0.46 |
| ▸ | HTR2B | P41595 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869024 | 1.00 | KMT2A (0.58) | KMT2ALMNANPC1RAB9AMEN1 | |
| SCHEMBL6868863 | 0.92 | KMT2A (0.56) | KMT2ALMNANPC1RAB9AMEN1 | |
| SCHEMBL6880458 | 0.92 | KMT2A (0.46) | KMT2ALMNANPC1RAB9AMEN1 | |
| SCHEMBL6868868 | 0.92 | KMT2A (0.56) | KMT2ALMNANPC1RAB9AMEN1 | |
| SCHEMBL6875979 | 0.91 | LMNA (0.54) | KMT2ALMNANPC1RAB9AMEN1 | |
| SCHEMBL6875974 | 0.91 | LMNA (0.54) | KMT2ALMNANPC1RAB9AMEN1 | |
| SCHEMBL7043216 | 0.86 | KMT2A (0.54) | KMT2ALMNANPC1RAB9AMEN1 | |
| SCHEMBL7043217 | 0.86 | KMT2A (0.54) | KMT2ALMNANPC1RAB9AMEN1 | |
| SCHEMBL6866433 | 0.86 | KMT2A (0.51) | KMT2ALMNANPC1RAB9AMEN1 | |
| SCHEMBL6866436 | 0.86 | KMT2A (0.51) | KMT2ALMNANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |