Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 9/20 | 0.44 |
| ▸ | ACACA | Q13085 | 8/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869049 | 1.00 | MCHR1 (0.51) | MCHR1ADRA2ANPY5RTSHRSMN1; SMN2 | |
| SCHEMBL6874026 | 0.90 | MEN1 (0.52) | MCHR1ADRA2ATSHRSMN1; SMN2HTR7 | |
| SCHEMBL6874029 | 0.90 | MEN1 (0.52) | MCHR1ADRA2ATSHRSMN1; SMN2HTR7 | |
| SCHEMBL6875316 | 0.86 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RACACBACACA | |
| SCHEMBL6878858 | 0.86 | MCHR1 (0.51) | MCHR1ADRA2ANPY5RACACBACACA | |
| SCHEMBL6878852 | 0.86 | MCHR1 (0.51) | MCHR1ADRA2ANPY5RACACBACACA | |
| SCHEMBL6875313 | 0.86 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RACACBACACA | |
| SCHEMBL6876478 | 0.84 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RSMN1; SMN2ACACB | |
| SCHEMBL6876486 | 0.84 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RSMN1; SMN2ACACB | |
| SCHEMBL6878308 | 0.84 | MCHR1 (0.47) | MCHR1ADRA2ANPY5RACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |