Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL6869306

O=c1ccc2ccc(OS(=O)(=O)c3c(F)c(F)c(F)c(F)c3F)cc2o1.S

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.63
GLA P06280 2/20 0.61
GAA P10253 2/20 0.61
STS P08842 1/20 0.61
CA12 O43570 13/20 0.51
CA1 P00915 13/20 0.51
CA9 Q16790 12/20 0.51
CA7 P43166 6/20 0.51
CA4 P22748 6/20 0.51
CA6 P23280 5/20 0.51
CA14 Q9ULX7 5/20 0.51
CA5A P35218 4/20 0.51
CA3 P07451 3/20 0.51
KDM4E B2RXH2 2/20 0.51
ALDH1A1 P00352 1/20 0.51
AKR1B1 P15121 1/20 0.51
HPGD P15428 1/20 0.51
HSD17B10 Q99714 1/20 0.51
CA5B Q9Y2D0 4/20 0.48
CYP1A2 P05177 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17318081 0.79 GLA (0.71) MAOBGLAGAASTSCA12
Hydrogen Sulfide SCHEMBL6878856 0.78 GLA (0.66) MAOBGLAGAASTSCA12
SCHEMBL10849811 0.77 MAOB (1.00) MAOBGLAGAASTSCA12
Hydrogen Sulfide SCHEMBL6880906 0.77 MAOB (0.73) MAOBGLAGAASTSCA12
SCHEMBL9432106 0.77 GLA (0.68) MAOBGLAGAASTSCA12
Hydrogen Sulfide SCHEMBL6875323 0.76 MAOB (0.68) MAOBGLAGAASTSCA12
SCHEMBL561434 0.76 GLA (1.00) MAOBGLAGAASTSCA12
7-Methanesulfonyloxycoumarin SCHEMBL10851014 0.76 GAA (0.71) MAOBGLAGAASTSCA12
SCHEMBL3367481 0.76 GLA (0.42) MAOBGLAGAASTSCA12
Potassium Ion SCHEMBL29669597 0.75 GLA (0.69) MAOBGLAGAASTSCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1481973-A1 HETEROCYCLE-BEARING ONIUM SALTS Wako Pure Chemical Industries, Ltd. (JP) 2004-12-01 EP disclosed