Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL6880906

Cc1ccc(S(=O)(=O)Oc2ccc3ccc(=O)oc3c2)cc1.S

nearest known ligand 0.73

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.73
CA12 O43570 6/20 0.68
CA1 P00915 4/20 0.68
CA9 Q16790 4/20 0.68
GLA P06280 4/20 0.63
GAA P10253 4/20 0.63
STS P08842 1/20 0.59
KDM4E B2RXH2 4/20 0.56
MAPT P10636 2/20 0.56
KMT2A Q03164 2/20 0.55
GBA1 P04062 1/20 0.55
MEN1 O00255 1/20 0.54
CA4 P22748 3/20 0.54
CA5A P35218 3/20 0.54
CA7 P43166 3/20 0.54
ALDH1A1 P00352 2/20 0.54
CA6 P23280 2/20 0.54
CA14 Q9ULX7 2/20 0.54
CA3 P07451 1/20 0.54
AKR1B1 P15121 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10849811 0.85 MAOB (1.00) MAOBCA12CA1CA9GLA
Hydrogen Sulfide SCHEMBL6875323 0.83 MAOB (0.68) MAOBCA12CA1CA9GLA
Hydrogen Sulfide SCHEMBL6877387 0.83 CA12 (0.54) MAOBCA12CA1CA9GLA
SCHEMBL8515482 0.81 CA12 (1.00) MAOBCA12CA1CA9GLA
SCHEMBL3523373 0.78 CA12 (0.58) MAOBCA12CA1CA9GLA
7-Methanesulfonyloxycoumarin SCHEMBL10851014 0.78 GAA (0.71) MAOBCA12CA1CA9GLA
SCHEMBL14802647 0.78 GBA1 (0.65) CA12CA1CA9GLAGAA
SCHEMBL561434 0.78 GLA (1.00) MAOBCA12CA1CA9GLA
SCHEMBL8794066 0.78 MEN1 (0.82) MAOBCA12GAAMAPTKMT2A
SCHEMBL4126086 0.77 MEN1 (0.60) CA12CA1CA9GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1481973-A1 HETEROCYCLE-BEARING ONIUM SALTS Wako Pure Chemical Industries, Ltd. (JP) 2004-12-01 EP disclosed