Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1950319 | 0.88 | TDP1 (0.57) | TDP1LMNAALOX15BLMPMP22 | |
| SCHEMBL28065487 | 0.84 | TDP1 (0.75) | TDP1LMNAALOX15BLMPMP22 | |
| Acetonitrile SCHEMBL491140 | 0.81 | — | — | |
| Dimethylketone Cyanohydrin SCHEMBL6474504 | 0.81 | LMNA (0.40) | TDP1LMNA | |
| Water SCHEMBL11248400 | 0.81 | — | — | |
| SCHEMBL1718040 | 0.79 | TDP1 (0.67) | TDP1LMNAALOX15BLMPMP22 | |
| Dimethylketone Cyanohydrin SCHEMBL11460654 | 0.78 | FFAR3 (0.44) | TDP1 | |
| Tert-Butylamine SCHEMBL7649267 | 0.78 | TDP1 (0.75) | TDP1LMNAALOX15BLMPMP22 | |
| Water SCHEMBL3263657 | 0.78 | — | — | |
| Water SCHEMBL28881049 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730177-B1 | CYANIDE TOLERANT NITRILHYDRATASES | EVONIK DEGUSSA GMBH (DE) | 2012-02-29 | — | — | EP | disclosed |
| EP-1730177-A2 | CYANIDE TOLERANT NITRILHYDRATASES | Degussa GmbH (DE) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005090394-A2 | CYANIDE TOLERANT NITRILHYDRATASES | DEGUSSA AG (DE) | 2005-09-29 | — | — | WO | disclosed |