Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696891 | 0.81 | TACR1 (0.56) | TACR1GPBAR1 | |
| SCHEMBL6016333 | 0.79 | TACR1 (0.56) | TACR1 | |
| SCHEMBL5779622 | 0.76 | TACR1 (0.75) | TACR1GPBAR1 | |
| SCHEMBL7702182 | 0.75 | TACR1 (0.60) | TACR1 | |
| SCHEMBL5782663 | 0.74 | TACR1 (0.72) | TACR1GPBAR1 | |
| SCHEMBL5966350 | 0.74 | TACR1 (0.80) | TACR1GPBAR1 | |
| SCHEMBL6862193 | 0.74 | TACR1 (0.80) | TACR1GPBAR1 | |
| Hydrochloric Acid SCHEMBL6869633 | 0.73 | TACR1 (0.78) | TACR1GPBAR1 | |
| SCHEMBL6862358 | 0.71 | TACR1 (0.72) | TACR1 | |
| SCHEMBL6869431 | 0.70 | TACR1 (0.52) | TACR1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187814-B1 | 5-PHENYL-PYRIMIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2004-08-18 | — | — | EP | disclosed |
| US-6756380-B1 | NEUROKININ 1 RECEPTOR ANTAGONISTS | HOFFMANN-LA ROCHE INC. | 2004-06-29 | — | — | US | disclosed |
| EP-1187814-A2 | 5-PHENYL-PYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000073278-A2 | 5-PHENYL-PYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-07 | — | — | WO | disclosed |