Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.85 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.69 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.69 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.68 |
| ▸ | PPARG | P37231 | 7/20 | 0.68 |
| ▸ | PPARD | Q03181 | 7/20 | 0.68 |
| ▸ | PPARA | Q07869 | 7/20 | 0.68 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.68 |
| ▸ | TSHR | P16473 | 4/20 | 0.68 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.68 |
| ▸ | TLR2 | O60603 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | FABP4 | P15090 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.68 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | ESR1 | P03372 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | PDE4A | P27815 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1877336 | 1.00 | ALDH1A1 (0.85) | ALDH1A1FFAR4FFAR1GPR84PPARG | |
| SCHEMBL1874171 | 1.00 | ALDH1A1 (0.85) | ALDH1A1FFAR4FFAR1GPR84PPARG | |
| SCHEMBL1882232 | 1.00 | ALDH1A1 (0.85) | ALDH1A1FFAR4FFAR1GPR84PPARG | |
| SCHEMBL1885207 | 1.00 | ALDH1A1 (0.85) | ALDH1A1FFAR4FFAR1GPR84PPARG | |
| SCHEMBL1878614 | 1.00 | ALDH1A1 (0.85) | ALDH1A1FFAR4FFAR1GPR84PPARG | |
| SCHEMBL1877224 | 1.00 | ALDH1A1 (0.85) | ALDH1A1FFAR4FFAR1GPR84PPARG | |
| SCHEMBL1874175 | 1.00 | ALDH1A1 (0.85) | ALDH1A1FFAR4FFAR1GPR84PPARG | |
| SCHEMBL1884098 | 1.00 | ALDH1A1 (0.85) | ALDH1A1FFAR4FFAR1GPR84PPARG | |
| SCHEMBL1879946 | 1.00 | ALDH1A1 (0.85) | ALDH1A1FFAR4FFAR1GPR84PPARG | |
| SCHEMBL1878619 | 1.00 | ALDH1A1 (0.85) | ALDH1A1FFAR4FFAR1GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6821301-B2 | AMPHOTERIC SURFACTANT AND/OR A CATIONIC SURFACTANT AND A BASE OIL AND HAS A SURFACE TENSION AT 25 DEGREES C. OF 14 TO 35 MN/M AND A SPECIFIC VOLUME RESISTIVITY | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2004-11-23 | — | — | US | disclosed |
| US-20030024052-A1 | Lubricants for elastic fiber | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2003-02-06 | — | — | US | disclosed |