SCHEMBL6869582

SCHEMBL6869582

O=S(=O)(O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=c1ccc2ccc(S)cc2o1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 5/20 0.43
GAA P10253 5/20 0.43
CA12 O43570 11/20 0.40
CA9 Q16790 10/20 0.40
CA1 P00915 6/20 0.40
KDM4E B2RXH2 5/20 0.40
ALDH1A1 P00352 4/20 0.40
AKR1B1 P15121 3/20 0.40
HPGD P15428 3/20 0.40
HSD17B10 Q99714 3/20 0.40
MCL1 Q07820 3/20 0.40
CASP1 P29466 2/20 0.40
CASP7 P55210 2/20 0.40
ERAP1 Q9NZ08 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
PGR P06401 1/20 0.40
STS P08842 1/20 0.37
MAPT P10636 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6875324 0.90 GLA (0.43) GLAGAACA12CA9CA1
Trifluoromethanesulfonic Acid SCHEMBL5114458 0.83 GLA (0.50) GLAGAACA12CA9CA1
SCHEMBL6880909 0.78 CA12 (0.49) GLAGAACA12CA9CA1
SCHEMBL6869309 0.76 GLA (0.47) GLAGAACA12CA9CA1
SCHEMBL6875856 0.76 GLA (0.44) GLAGAACA12CA9CA1
SCHEMBL5040810 0.76 CA12 (0.59) GLAGAACA12CA9CA1
Bromide SCHEMBL6878726 0.74 CA12 (0.57) GLAGAACA12CA9CA1
SCHEMBL3371852 0.73 MAOB (0.41) GLAGAACA12CA9CA1
SCHEMBL6869587 0.73 GLA (0.41) GLAGAACA12CA9CA1
SCHEMBL5866898 0.73 GLA (0.58) GLAGAACA12CA9CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1481973-A1 HETEROCYCLE-BEARING ONIUM SALTS Wako Pure Chemical Industries, Ltd. (JP) 2004-12-01 EP disclosed