SCHEMBL6869587

SCHEMBL6869587

O=c1ccc2ccc(SOS(=O)(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)cc2o1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 4/20 0.41
GAA P10253 3/20 0.41
MAOB P27338 2/20 0.41
STS P08842 1/20 0.39
PGR P06401 1/20 0.38
CA12 O43570 11/20 0.36
CA1 P00915 10/20 0.36
CA9 Q16790 10/20 0.36
CA7 P43166 5/20 0.36
KDM4E B2RXH2 4/20 0.36
CA4 P22748 4/20 0.36
CA5A P35218 4/20 0.36
CA6 P23280 4/20 0.36
CA14 Q9ULX7 4/20 0.36
ALDH1A1 P00352 3/20 0.36
AKR1B1 P15121 2/20 0.36
HPGD P15428 2/20 0.36
HSD17B10 Q99714 2/20 0.36
CA3 P07451 2/20 0.36
MCL1 Q07820 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5114461 0.80 GLA (0.43) GLAGAAMAOBSTSCA12
SCHEMBL3371852 0.79 MAOB (0.41) GLAGAAMAOBSTSPGR
SCHEMBL3525107 0.74 MAOB (0.49) GLAGAAMAOBSTSPGR
SCHEMBL6869582 0.73 GLA (0.43) GLAGAAMAOBSTSPGR
SCHEMBL3371848 0.70 PGR (0.39) GLAGAAMAOBSTSPGR
SCHEMBL15842571 0.70 PGR (0.58) GLAGAASTSPGRCA12
SCHEMBL3367177 0.69 MAOB (0.43) GLAGAAMAOBSTSPGR
SCHEMBL5045519 0.69 PGR (0.45) GLAGAASTSPGRCA12
Hydrogen Sulfide SCHEMBL6875323 0.68 MAOB (0.68) GLAGAAMAOBSTSCA12
SCHEMBL3525103 0.67 MAOB (0.41) GLAGAAMAOBSTSPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1481973-A1 HETEROCYCLE-BEARING ONIUM SALTS Wako Pure Chemical Industries, Ltd. (JP) 2004-12-01 EP disclosed