Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CPA3 | P15088 | 3/20 | 0.60 |
| ▸ | CPA1 | P15085 | 5/20 | 0.57 |
| ▸ | CPB1 | P15086 | 1/20 | 0.54 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2121039 | 0.98 | FOLH1 (0.68) | FOLH1CYP1A2CPA3CPA1CPB1 | |
| SCHEMBL8868174 | 0.87 | FOLH1 (0.54) | FOLH1CYP1A2CPA3CPA1 | |
| SCHEMBL1114629 | 0.86 | CYP1A2 (0.70) | FOLH1CYP1A2CPA3CPA1CPB1 | |
| SCHEMBL11664393 | 0.86 | FOLH1 (0.79) | FOLH1CYP1A2CPA3CPA1CPB1 | |
| SCHEMBL8868645 | 0.85 | GRIK1 (0.51) | FOLH1CYP1A2CPA1CPB2 | |
| SCHEMBL8867961 | 0.85 | GRIK1 (0.51) | FOLH1CYP1A2CPA1CPB2 | |
| SCHEMBL8867562 | 0.85 | GRIK1 (0.51) | FOLH1CYP1A2CPA1CPB2 | |
| SCHEMBL10521559 | 0.85 | FOLH1 (0.68) | FOLH1CYP1A2CPA3CPA1CPB1 | |
| SCHEMBL2455434 | 0.85 | FOLH1 (0.68) | FOLH1CYP1A2CPA3CPA1CPB1 | |
| SCHEMBL23234369 | 0.83 | FOLH1 (0.66) | FOLH1CYP1A2CPA3CPA1CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105399-B1 | CARBOXYLATED PHOSPHATIDIC ACID ESTERS | BRACCO RESEARCH SA (CH) | 2004-04-14 | — | — | EP | disclosed |
| US-6706280-B2 | DRUG TARGETING WITH LIPOSOMES AND MAGNETIC RESONANCE IMAGING CONTRAST MEDIA FOR DIAGNOSTICS | BRACCO RESEARCH S.A. (CH) | 2004-03-16 | — | — | US | disclosed |
| US-20020136760-A1 | CARBOXYLATED PHOSPHATIDIC ACID ESTERS | BRACCO RESEARCH S.A. (CH) | 2002-09-26 | — | — | US | disclosed |
| EP-1105399-A1 | CARBOXYLATED PHOSPHATIDIC ACID ESTERS | BRACCO RESEARCH S.A. (CH) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000011007-A1 | CARBOXYLATED PHOSPHATIDIC ACID ESTERS | BRACCO RESEARCH S.A. (CH) | 2000-03-02 | — | — | WO | disclosed |
| US-5599966-A | SUITABLE FOR TREATMENT OF DISEASES OF RESPIRATORY PASSAGES | BYK NEDERLAND BV (NL) | 1997-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020136760-A1 | CARBOXYLATED PHOSPHATIDIC ACID ESTERS | PHOSPHO1, PLD1, SGMS1 | FOLH1 436/4885CYP1A2 2085/4885CPA3 924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.