Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.51 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | LAP3 | P28838 | 2/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867961 | 1.00 | GRIK1 (0.51) | GRIK1CPB2FOLH1MMP2MMP3 | |
| SCHEMBL8867562 | 1.00 | GRIK1 (0.51) | GRIK1CPB2FOLH1MMP2MMP3 | |
| SCHEMBL8868315 | 0.92 | GRIK1 (0.56) | GRIK1CPB2FOLH1MMP2MMP3 | |
| SCHEMBL1862995 | 0.86 | GRIK1 (0.61) | GRIK1CPB2FOLH1MMP2MMP3 | |
| SCHEMBL6869749 | 0.85 | FOLH1 (0.66) | CPB2FOLH1CYP1A2CPA1 | |
| SCHEMBL1860416 | 0.84 | GRIK1 (0.68) | GRIK1CPB2FOLH1MMP2MMP3 | |
| SCHEMBL1857365 | 0.84 | CYP1A2 (0.61) | GRIK1CPB2FOLH1CYP1A2CPA1 | |
| SCHEMBL8905261 | 0.84 | MMP2 (0.55) | GRIK1CPB2MMP2MMP3 | |
| SCHEMBL8775151 | 0.84 | MAPT (0.64) | GRIK1CPB2FOLH1 | |
| SCHEMBL1716640 | 0.84 | MMP2 (0.55) | GRIK1CPB2MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599966-A | SUITABLE FOR TREATMENT OF DISEASES OF RESPIRATORY PASSAGES | BYK NEDERLAND BV (NL) | 1997-02-04 | — | — | US | disclosed |