Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 6/20 | 0.61 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA6 | P23280 | 1/20 | 0.59 |
| ▸ | CA5A | P35218 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.59 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | MGLL | Q99685 | 2/20 | 0.56 |
| ▸ | F11 | P03951 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5906831 | 0.91 | CA1 (0.64) | LPLLIPGCA4CA6CA5A | |
| SCHEMBL890400 | 0.90 | LPL (0.73) | LPLLIPGCA4CA6CA5A | |
| SCHEMBL257769 | 0.86 | CA4 (0.59) | LPLLIPGCA4CA6CA5A | |
| SCHEMBL8124493 | 0.81 | TRPV1 (0.48) | LPLLIPGCA4CA6CA5A | |
| SCHEMBL29958276 | 0.81 | TRPV1 (0.48) | LPLLIPGCA4CA6CA5A | |
| SCHEMBL12663169 | 0.80 | CA4 (0.52) | LPLLIPGCA4CA6CA5A | |
| SCHEMBL178228 | 0.80 | TSHR (0.62) | LPLLIPGCA4CA6CA5A | |
| SCHEMBL6356134 | 0.80 | TRPV1 (0.58) | LPLLIPGCA4CA6CA5A | |
| SCHEMBL12031460 | 0.80 | CA4 (0.52) | LPLLIPGCA4CA6CA5A | |
| SCHEMBL12011034 | 0.79 | LPL (0.73) | LPLLIPGENPP2TRPV1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1004578-B1 | 5-oxo-pyrrolidine-2-carboxylic acid hydroxamide derivatives | PFIZER PROD INC (US) | 2004-02-25 | — | — | EP | disclosed |
| US-6114361-A | INHIBITORS OF MATRIX METALLOPROTEINASES AND REPROLYSIN; ADMINISTERING TO TREAT CONDITIONS WHICH CAN BE TREATED BY THE INHIBITION OF THESE ENZYMES | PFIZER INC. (US) | 2000-09-05 | — | — | US | disclosed |
| EP-1004578-A2 | 5-oxo-pyrrolidine-2-carboxylic acid hydroxamide derivatives | Pfizer Products Inc. (US) | 2000-05-31 | — | — | EP | disclosed |