SCHEMBL686993

SCHEMBL686993

CCO[Si](CCCNC(C)=O)(OCC)OCC

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.52
MAPK1 P28482 1/20 0.52
HIF1A Q16665 1/20 0.52
PAOX Q6QHF9 3/20 0.47
ADRA1A P35348 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.40
TSHR P16473 1/20 0.39
ALDH1A1 P00352 1/20 0.38
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ACACB O00763 1/20 0.35
ACHE P22303 1/20 0.34
EPHX1 P07099 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7556625 0.88 KDM4E (0.39) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL17111035 0.88 KDM4E (0.44) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL2561394 0.86 EPHX1 (0.48) TSHRCA12CA1CA2CA9
SCHEMBL25344192 0.86 CA12 (0.37) ALDH1A1CA12CA1CA2CA9
SCHEMBL12742202 0.85 KDM4E (0.41) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL7122081 0.84 MEN1 (0.45) TSHRALDH1A1CA12CA1CA2
SCHEMBL4419366 0.84 EPHX1 (0.47) TSHRCA12CA1CA2CA9
SCHEMBL2145050 0.84 EGLN1 (0.37) ALDH1A1CA12CA1CA2CA9
SCHEMBL10481544 0.83 MEN1 (0.41) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL2616729 0.82 KDM4E (0.50) KDM4EMAPK1HIF1APAOXADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025122886-A1 SYSTEMS FOR SUPERELASTIC SPLINES WITH POLYMER INSULATION ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC. (US) 2025-06-12 WO claimed
CN-115895583-B Under-coating-free dealcoholized single-component room temperature vulcanized silicone rubber for hydrophilic aluminum foil water-resistant adhesion and preparation method thereof 广州集泰化工股份有限公司 2025-03-04 CN claimed
CN-115895583-A Primer-free dealcoholized single-component room temperature vulcanized silicone rubber for waterproof bonding of hydrophilic aluminum foil and preparation method thereof 广州集泰化工股份有限公司 2023-04-04 CN claimed
US-20030157391-A1 Silane coated metallic fuel cell components and methods of manufacture GENCELL CORPORATION 2003-08-21 US claimed
WO-2003067682-A2 SILANE COATED METALLIC FUEL CELL COMPONENTS AND METHODS OF MANUFACTURE GENCELL CORPORATION (US) 2003-08-14 WO claimed
US-4298500-A Mixed phase chromatographic compositions VARIAN ASSOCIATES, INC. (US) 1981-11-03 US claimed
WO-2025122886-A1 SYSTEMS FOR SUPERELASTIC SPLINES WITH POLYMER INSULATION ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC. (US) 2025-06-12 WO disclosed
CN-115895583-B Under-coating-free dealcoholized single-component room temperature vulcanized silicone rubber for hydrophilic aluminum foil water-resistant adhesion and preparation method thereof 广州集泰化工股份有限公司 2025-03-04 CN disclosed
US-11795058-B2 Silicon dioxide composite particle with far-infrared radioactivity; precursor of the same and application thereof NATIONAL CHI NAN UNIVERSITY (TW) 2023-10-24 US disclosed
US-20230310696-A1 BIODEGRADABLE BONE GLUE EVONIK OPERATIONS GMBH (DE) 2023-10-05 US disclosed
US-20230310696-A1 BIODEGRADABLE BONE GLUE EVONIK OPERATIONS GMBH (DE) 2023-10-05 US disclosed
CN-115895583-A Primer-free dealcoholized single-component room temperature vulcanized silicone rubber for waterproof bonding of hydrophilic aluminum foil and preparation method thereof 广州集泰化工股份有限公司 2023-04-04 CN disclosed
CN-113248367-B Method for realizing continuous production of acyl chloride compound by catalysis of immobilized organic base 东南大学 2022-04-26 CN disclosed
WO-2006079516-A2 A BINDER COMPOSITION SIGMA COATINGS B.V. (NL) 2006-08-03 WO disclosed
US-20030157391-A1 Silane coated metallic fuel cell components and methods of manufacture GENCELL CORPORATION 2003-08-21 US disclosed
WO-2003067682-A2 SILANE COATED METALLIC FUEL CELL COMPONENTS AND METHODS OF MANUFACTURE GENCELL CORPORATION (US) 2003-08-14 WO disclosed
EP-0161058-B1 DUAL SURFACE MATERIALS DOW CORNING CORPORATION (US) 1989-05-24 EP disclosed
US-4542174-A NONHYDROLYZING, STORAGE STABLE UNION CARBIDE CORPORATION (US) 1985-09-17 US disclosed
US-4298500-A Mixed phase chromatographic compositions VARIAN ASSOCIATES, INC. (US) 1981-11-03 US disclosed
US-3940357-A ELASTOMER LATEX, ZINC SALT PPG INDUSTRIES, INC. (US) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11795058-B2 Silicon dioxide composite particle with far-infrared radioactivity; precursor of the same and application thereof MSR1, SIK2, FAR1 KDM4E 4799/4885MAPK1 4152/4885HIF1A 1100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.