Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.62 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.62 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677603 | 0.93 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1TDP1SLC7A5 | |
| SCHEMBL28015104 | 0.83 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1TDP1SLC7A5 | |
| SCHEMBL2717757 | 0.83 | SLC1A3 (0.62) | SLC1A3SLC1A2SLC1A1TDP1SLC7A5 | |
| SCHEMBL9213452 | 0.81 | SLC1A3 (0.60) | SLC1A3SLC1A2SLC1A1TDP1SLC7A5 | |
| SCHEMBL9858433 | 0.81 | SLC1A3 (0.60) | SLC1A3SLC1A2SLC1A1TDP1SLC7A5 | |
| SCHEMBL26138067 | 0.79 | SLC1A3 (0.58) | SLC1A3SLC1A2SLC1A1TDP1SLC7A5 | |
| SCHEMBL1389820 | 0.77 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1TDP1SLC7A5 | |
| SCHEMBL27818839 | 0.77 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1TDP1SLC7A5 | |
| SCHEMBL11591560 | 0.77 | ACE (0.50) | SLC1A3SLC1A2SLC1A1TDP1SLC7A5 | |
| SCHEMBL9005541 | 0.77 | SLC1A2 (1.00) | SLC1A3SLC1A2SLC1A1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011070459-A1 | PROCESS FOR ENANTIOMERICALLY PURE 8-ARYLOCTANOIC ACIDS AS ALISKIREN | CarboDesign LLC (US) | 2011-06-16 | — | — | WO | disclosed |