Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.60 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.60 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.60 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3755208 | 0.82 | NAALAD2 (0.45) | SLC1A3SLC1A2SLC1A1NAALAD2FOLH1 | |
| SCHEMBL30018466 | 0.82 | NAALAD2 (0.45) | SLC1A3SLC1A2SLC1A1NAALAD2FOLH1 | |
| SCHEMBL2717757 | 0.81 | SLC1A3 (0.62) | SLC1A3SLC1A2SLC1A1TDP1RNPEP | |
| SCHEMBL6870066 | 0.81 | SLC1A3 (0.62) | SLC1A3SLC1A2SLC1A1NAALAD2FOLH1 | |
| SCHEMBL10938417 | 0.80 | NAALAD2 (0.56) | NAALAD2FOLH1ENPEPGABRR1CYP1A2 | |
| SCHEMBL443229 | 0.80 | NAALAD2 (0.56) | NAALAD2FOLH1ENPEPGABRR1CYP1A2 | |
| SCHEMBL7314519 | 0.80 | NAALAD2 (0.56) | NAALAD2FOLH1ENPEPGABRR1CYP1A2 | |
| SCHEMBL21052495 | 0.79 | GABRR1 (0.54) | SLC1A3SLC1A2SLC1A1NAALAD2FOLH1 | |
| SCHEMBL9858433 | 0.79 | SLC1A3 (0.60) | SLC1A3SLC1A2SLC1A1NAALAD2FOLH1 | |
| SCHEMBL6631364 | 0.78 | NAALAD2 (0.42) | SLC1A3SLC1A2SLC1A1NAALAD2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0681582-A1 | PYRAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-15 | — | — | EP | disclosed |