SCHEMBL6870260

SCHEMBL6870260

COC(=N)CC(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4532985 0.97
SCHEMBL25023926 0.72
SCHEMBL4004854 0.72
SCHEMBL8765419 0.72
SCHEMBL19956318 0.70
Hydrochloric Acid SCHEMBL3484169 0.70 ALDH1A1 (0.32)
Hydrochloric Acid SCHEMBL4521898 0.70 CA1 (0.37)
SCHEMBL6735677 0.70
Hydrochloric Acid SCHEMBL9460501 0.69
SCHEMBL11275226 0.67 ALDH1A1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11913071-B2 Methods and compositions for sequencing complementary polynucleotides Singular Genomics Systems, Inc. (US) 2024-02-27 US disclosed
US-20240026428-A1 METHODS FOR IN SITU TRANSCRIPTOMICS AND PROTEOMICS FIRST-CITIZENS BANK & TRUST COMPANY 2024-01-25 US disclosed
US-20230399692-A1 NUCLEIC ACID DELIVERY SCAFFOLDS FIRST-CITIZENS BANK & TRUST COMPANY 2023-12-14 US disclosed
US-20230366013-A1 SPATIAL SEQUENCING FIRST-CITIZENS BANK & TRUST COMPANY 2023-11-16 US disclosed
US-20230357828-A1 SPATIAL SEQUENCING OF MODIFIED SEQUENCES FIRST-CITIZENS BANK & TRUST COMPANY 2023-11-09 US disclosed
US-11795505-B2 Nucleic acid delivery scaffolds Singular Genomics Systems, Inc. (US) 2023-10-24 US disclosed
US-11788133-B2 Methods and compositions for sequencing complementary polynucleotides Singular Genomics Systems, Inc. (US) 2023-10-17 US disclosed
US-20230295437-A1 SILICON CONTAINING DETECTABLE COMPOUNDS Singular Genomics Systems, Inc. 2023-09-21 US disclosed
US-20230287491-A1 NUCLEIC ACID DELIVERY SCAFFOLDS FIRST-CITIZENS BANK & TRUST COMPANY 2023-09-14 US disclosed
US-11753678-B2 Spatial sequencing Singular Genomics Systems, Inc. (US) 2023-09-12 US disclosed
US-20230160001-A1 NUCLEOTIDE CLEAVABLE LINKERS WITH RIGID SPACERS AND USES THEREOF FIRST-CITIZENS BANK & TRUST COMPANY 2023-05-25 US disclosed
US-11649452-B2 High density sequencing and multiplexed priming Singular Genomics Systems, Inc. (US) 2023-05-16 US disclosed
US-11643679-B2 Methods for in situ transcriptomics and proteomics SINGULAR GENOMICS SYTEMS, INC. (US) 2023-05-09 US disclosed
US-9644195-B2 Compounds and methods for purification of serine proteases PORTOLA PHARMACEUTICALS, INC. (US) 2017-05-09 US disclosed
US-9200268-B2 Compounds and methods for purification of serine proteases PORTOLA PHARMACEUTICALS, INC. (US) 2015-12-01 US disclosed
US-20150337285-A1 COMPOUNDS AND METHODS FOR PURIFICATION OF SERINE PROTEASES ALEXION PHARMA INTERNATIONAL OPERATIONS UNLIMITED COMPANY (IE) 2015-11-26 US disclosed
US-20150175998-A1 Methods and Kits to Create Protein Substrate˜HECT-Ubiquitin Ligase Pairs NORTHWESTERN UNIVERSITY 2015-06-25 US disclosed
US-20140346397-A1 COMPOUNDS AND METHODS FOR PURIFICATION OF SERINE PROTEASES ALEXION PHARMA INTERNATIONAL OPERATIONS UNLIMITED COMPANY (IE) 2014-11-27 US disclosed
US-20140186923-A1 COMPOUNDS AND METHODS FOR PURIFICATION OF SERINE PROTEASES PORTOLA PHARMACEUTICALS, INC. (US) 2014-07-03 US disclosed
US-6806380-B2 SUCH AS 1-METHOXY-2-(3-METHYLPHENYL)ETHANIMINE BY TREATING NITRILE WITH ANHYDROUS HYDROGEN CHLORIDE SOLUTION AND ANHYDROUS ALCOHOL LEXICON PHARMACEUTICALS, INC. 2004-10-19 US disclosed