Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8131755 | 0.85 | CHRM1 (0.50) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL9861670 | 0.84 | GPR84 (0.42) | TSHRFDPS | |
| SCHEMBL452330 | 0.84 | TDP1 (0.46) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL15455666 | 0.81 | TDP1 (0.43) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL223020 | 0.79 | CHRM1 (0.55) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL11587400 | 0.79 | CHRM1 (0.55) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL11469120 | 0.78 | CA1 (0.36) | TDP1TSHRALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL8135518 | 0.77 | CHRM1 (0.52) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL5269712 | 0.77 | CHRM1 (0.52) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL28484976 | 0.77 | CHRM1 (0.52) | TDP1CHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073997-A2 | PROCESS FOR PREPARING PALIPERIDONE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2011-06-23 | — | — | WO | disclosed |