Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 13/20 | 0.55 |
| ▸ | HTR2A | P28223 | 4/20 | 0.51 |
| ▸ | HTR2C | P28335 | 4/20 | 0.51 |
| ▸ | HTR2B | P41595 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6868251 | 0.88 | HRH2 (0.56) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6872041 | 0.87 | HRH2 (0.55) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6782121 | 0.87 | HRH2 (0.57) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6872329 | 0.83 | DRD2 (0.50) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6781803 | 0.79 | HRH2 (0.65) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6782119 | 0.78 | HRH2 (0.64) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6776868 | 0.77 | HRH2 (0.71) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6775396 | 0.77 | HRH2 (0.67) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6781653 | 0.76 | HRH2 (0.78) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL7156393 | 0.75 | HRH2 (0.65) | HRH2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183251-B1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA SA (ES) | 2004-02-11 | — | — | EP | claimed |