Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 10/20 | 0.46 |
| ▸ | CTSA | P10619 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687906 | 0.93 | PTGER3 (0.47) | PTGER3CTSAMAPTITGB1ITGA4 | |
| SCHEMBL687732 | 0.91 | PTGER3 (0.49) | PTGER3CTSAMAPTCYP1A2 | |
| SCHEMBL688040 | 0.90 | PTGER3 (0.49) | PTGER3CTSAMAPTCYP1A2 | |
| SCHEMBL688155 | 0.90 | PTGER3 (0.49) | PTGER3CTSAMAPTCYP1A2 | |
| SCHEMBL687971 | 0.89 | FFAR1 (0.42) | PTGER3CTSAITGB1ITGA4CYP1A2 | |
| SCHEMBL687647 | 0.88 | PTGER3 (0.44) | PTGER3MAPTCYP1A2 | |
| SCHEMBL687418 | 0.88 | PTGER3 (0.46) | PTGER3CYP1A2 | |
| SCHEMBL688004 | 0.87 | PTGER3 (0.44) | PTGER3CTSA | |
| SCHEMBL687771 | 0.86 | PTGER3 (0.45) | PTGER3CYP1A2 | |
| SCHEMBL687155 | 0.86 | PTGER3 (0.44) | PTGER3ITGB1ITGA4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |