Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 9/20 | 0.47 |
| ▸ | CTSA | P10619 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688040 | 0.97 | PTGER3 (0.49) | PTGER3CTSAKDM4EALDH1A1MAPK1 | |
| SCHEMBL688155 | 0.97 | PTGER3 (0.49) | PTGER3CTSAKDM4EALDH1A1MAPK1 | |
| SCHEMBL687129 | 0.93 | PTGER3 (0.46) | PTGER3CTSAMAPTITGB1ITGA4 | |
| SCHEMBL687418 | 0.91 | PTGER3 (0.46) | PTGER3KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL687681 | 0.91 | CTSA (0.42) | PTGER3CTSAKDM4EALDH1A1MAPK1 | |
| SCHEMBL688004 | 0.90 | PTGER3 (0.44) | PTGER3CTSAKDM4EALDH1A1MAPK1 | |
| SCHEMBL686762 | 0.90 | PTGER3 (0.51) | PTGER3CTSAKDM4EALDH1A1MAPK1 | |
| SCHEMBL687647 | 0.90 | PTGER3 (0.44) | PTGER3KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL686620 | 0.90 | PTGER3 (0.50) | PTGER3CTSAKDM4EALDH1A1MAPK1 | |
| SCHEMBL686961 | 0.89 | PTGER3 (0.48) | PTGER3CTSAKDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |