Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.60 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | HTR2B | P41595 | 4/20 | 0.54 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorene SCHEMBL28112745 | 0.93 | MAOA (0.58) | SRD5A2MAOAHTR2BHTR2CHTR7 | |
| Fluorene SCHEMBL27918830 | 0.92 | SRD5A2 (0.53) | SRD5A2MAOAHTR2BHTR2CHTR7 | |
| Fluorene SCHEMBL8840919 | 0.90 | SRD5A2 (0.64) | SRD5A2MAOAHTR2BHTR2CHTR7 | |
| Fluorene SCHEMBL27734317 | 0.90 | SRD5A2 (0.51) | SRD5A2MAOAHTR2BHTR2CHTR7 | |
| Fluorene SCHEMBL27662337 | 0.88 | HTR2B (0.56) | SRD5A2MAOAHTR2BHTR2CHTR7 | |
| Fluorene SCHEMBL27664493 | 0.88 | MAOA (0.54) | SRD5A2MAOAHTR2BHTR2CHTR7 | |
| Fluorene SCHEMBL27907188 | 0.86 | SRD5A2 (0.60) | SRD5A2MAOAHTR2BHTR2CHTR7 | |
| Fluorene SCHEMBL2131210 | 0.86 | SRD5A2 (0.60) | SRD5A2MAOAHTR2BHTR2CHTR7 | |
| Fluorene SCHEMBL27791149 | 0.85 | MAOA (0.67) | SRD5A2MAOAHTR2BHTR2CHTR7 | |
| Fluorene SCHEMBL14118022 | 0.84 | MAOA (0.65) | SRD5A2MAOAKDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103328532-B | Reagents for Targeted Biomarker Signal Amplification | SIRIGEN INC. (GB) | 2016-05-25 | — | — | CN | disclosed |
| CN-102660201-B | Comprise the optical element of anisotropic conductive film | Daiichi Woolen Co.,Ltd. (KR) | 2015-09-02 | — | — | CN | disclosed |
| CN-102660201-A | Optical member comprising anisotropic conductive film | CHEIL IND INC | 2012-09-12 | — | — | CN | disclosed |
| US-6683201-B2 | FOR THERAPY AND PROPHYLAXIS OF HYPERCHOLESTEROLEMIA, HYPERLIPEMIA, ARTERIOSCLEROSIS, VASCULAR DISEASES, MYCOSES, PARASITE INFECTIONS, GALLSTONES, TUMORS AND/OR HYPERPROLIFERATIVE DISORDERS, DIABETES | HOFFMANN-LA ROCHE INC. | 2004-01-27 | — | — | US | disclosed |