Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6871378 | 0.91 | ADORA2A (0.64) | ADORA2AL3MBTL1PDE11A | |
| SCHEMBL6863049 | 0.90 | ADORA2A (0.45) | ADORA2AMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL6870657 | 0.89 | ADORA2A (0.50) | ADORA2AALDH1A1HPGDHDAC6PDE11A | |
| SCHEMBL6870319 | 0.86 | ADORA2A (0.49) | ADORA2AHPGDPDE11A | |
| SCHEMBL6871576 | 0.85 | ADORA2A (0.44) | ADORA2AHPGDPDE11A | |
| SCHEMBL6866988 | 0.84 | ADORA2A (0.60) | ADORA2AHPGDPDE11A | |
| SCHEMBL6872164 | 0.84 | ADORA2A (0.59) | ADORA2AMEN1KMT2AALDH1A1APOBEC3A | |
| SCHEMBL6870506 | 0.84 | ADORA2A (0.55) | ADORA2AMEN1KMT2AALDH1A1 | |
| SCHEMBL6871912 | 0.83 | ADORA2A (0.60) | ADORA2AHPGDPDE11A | |
| SCHEMBL6869917 | 0.83 | ADORA2A (0.58) | ADORA2AMEN1KMT2AALDH1A1APOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |