Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | VCAM1 | P19320 | 11/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29563244 | 1.00 | TDP1 (0.59) | TDP1ATMVCAM1TSHRMAPK1 | |
| SCHEMBL6368 | 0.83 | TDP1 (0.64) | TDP1ATMVCAM1TSHRMAPK1 | |
| SCHEMBL29537379 | 0.83 | TDP1 (0.64) | TDP1ATMVCAM1TSHRMAPK1 | |
| Fluoride SCHEMBL27762448 | 0.82 | TDP1 (0.62) | TDP1ATMVCAM1TSHRMAPK1 | |
| SCHEMBL4617709 | 0.81 | VCAM1 (0.61) | VCAM1NPBWR1MCHR1ALDH1A1 | |
| SCHEMBL29745239 | 0.80 | TDP1 (0.72) | TDP1ATMVCAM1TSHRMAPK1 | |
| SCHEMBL216553 | 0.80 | TDP1 (0.72) | TDP1ATMVCAM1TSHRMAPK1 | |
| SCHEMBL9808949 | 0.79 | VCAM1 (0.45) | TDP1ATMVCAM1TSHRMAPK1 | |
| SCHEMBL11866035 | 0.79 | VCAM1 (0.45) | TDP1ATMVCAM1TSHRMAPK1 | |
| SCHEMBL2497587 | 0.79 | MAPT (0.46) | TDP1ATMTSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110498730-A | A kind of synthetic method of 1,2,4- trifluoro-benzene | ZHEJIANG LINJIANG CHEMICAL CO LTD | 2019-11-26 | — | — | CN | claimed |
| CN-109400459-A | The preparation method of 2,4,5- trifluoro benzene acetic acid | 浙江工业大学上虞研究院有限公司 | 2019-03-01 | — | — | CN | claimed |
| CN-105646140-B | A kind of preparation method of 1,2,4,5- phenyl tetrafluorides | 浙江工业大学 | 2018-06-29 | — | — | CN | claimed |
| EP-0635481-B1 | Process for the preparation of fluoronitrobenzenes | CLARIANT GMBH (DE) | 1998-12-09 | — | — | EP | claimed |
| EP-0667337-B1 | Method for preparing fluoroanilines | CLARIANT GMBH (DE) | 1998-01-21 | — | — | EP | claimed |
| US-5498794-A | Process for preparing fluoroanilines | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | claimed |
| US-5476976-A | Process for preparing fluoronitrobenzenes | HOECHST AG (DE) | 1995-12-19 | — | — | US | claimed |
| EP-0667337-A1 | Method for preparing fluoroanilines | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-16 | — | — | EP | claimed |
| EP-0635481-A2 | Process for the preparation of fluoronitrobenzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-01-25 | — | — | EP | claimed |
| JP-60013743-A | — | — | None | — | — | JP | disclosed |
| US-20240366770-A1 | DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE SWITZERLAND GMBH (CH) | 2024-11-07 | — | — | US | disclosed |
| EP-4457230-A1 | DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BeiGene Switzerland GmbH (CH) | 2024-11-06 | — | — | EP | disclosed |
| CN-113710654-B | Polymerizable liquid crystal having carbazole nucleus | 罗利克技术有限公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-118414336-A | Degradation of Bruton Tyrosine Kinase (BTK) by conjugation of BTK inhibitors to E3 ligase ligands and methods of use | 百济神州有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-1011587-B | PROCESS FOR THE PREPARATION OF QUINOLONECARBOXYLIC ACID DERIVATIVES AND THEIR USE | KYORIN SEIYAKU KK (JP) | 1991-02-13 | — | — | CN | disclosed |
| CN-1007150-B | SYNTHESIS OF 2,4-DICHLOR-5-FLUOR BENZOIC ACID | TIANJIN PHARMACEUTIC INDUSTRY (CN) | 1990-03-14 | — | — | CN | disclosed |
| CN-1031074-A | 2,4-two chloro-5-fluorobenzoic acids synthetic | TIANJIN RESEARCH INST OF MEDIC (CN) | 1989-02-15 | — | — | CN | disclosed |
| CN-86102363-A | The preparation method of Carbostyril carboxylic acid derivatives and application thereof | — | 1987-01-21 | — | — | CN | disclosed |
| CN-85109026-A | The preparation method and its usage of Carbostyril carboxylic acid derivatives | — | 1986-07-30 | — | — | CN | disclosed |
| JP-S6013743-A | PRODUCTION OF 2,5-DIFLUORONITROBENZENE | TOYO SODA MFG CO LTD | 1985-01-24 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240366770-A1 | DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BTK, CBL, LYN | TDP1 1215/4885ATM 1032/4885VCAM1 1587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.