Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11022319 | 0.78 | ALDH1A1 (0.44) | APPALDH1A1KDM4ELMNACA1 | |
| SCHEMBL3813443 | 0.76 | ALDH1A1 (0.44) | ALDH1A1KDM4ELMNACA1CA2 | |
| SCHEMBL9499893 | 0.76 | HSD17B10 (0.42) | AOC3CES2CES1ALDH1A1KDM4E | |
| SCHEMBL19492956 | 0.76 | KCNN4 (0.33) | APPALDH1A1KDM4EKCNN4MEN1 | |
| SCHEMBL2455066 | 0.75 | ALDH1A1 (0.39) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL18379998 | 0.72 | ESR1 (0.31) | APPAOC3ALDH1A1ESR1ESR2 | |
| SCHEMBL9502559 | 0.71 | CHRM5 (0.42) | LOXL2ALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL10906048 | 0.71 | — | — | |
| SCHEMBL2096896 | 0.71 | APP (0.48) | APPAOC3CES1KDM4EACHE | |
| SCHEMBL8002775 | 0.71 | MAPT (0.49) | APPAOC3CES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693665-B | Hydrazone derivative of the ring containing benzofuran and preparation method thereof and medical usage | 湖南大学 | 2018-02-09 | — | — | CN | disclosed |
| CN-102725281-A | Azole derivatives as WTN pathway inhibitors | OSLO UNIVERSITY HOSPITAL HF | 2012-10-10 | — | — | CN | disclosed |
| CN-102574883-A | Organometallic complex, light-emitting element, display device, electronic device, and lighting device | SEMICONDUCTOR ENERGY LAB | 2012-07-11 | — | — | CN | disclosed |
| EP-1149094-B1 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2004-04-21 | — | — | EP | disclosed |
| US-6376491-B1 | BENZOFURAN DERIVATIVES FOR TREATMENT OR PREVENTION OF MYCOSIS IN MAMMALS | BASILEA PHARMACEUTICA AG (CH) | 2002-04-23 | — | — | US | disclosed |
| EP-1149094-A2 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | Basilea Pharmaceutica AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000037464-A2 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2000-06-29 | — | — | WO | disclosed |
| CN-1251589-A | Substituted triazolopyridazine derivatives as ligands for GABA receptors | MERCK SHARP & DOHME (GB) | 2000-04-26 | — | — | CN | disclosed |
| EP-0536345-A1 | PHOTOGRAPHIC HIGH CONTRAST SILVER HALIDE MATERIALS | KODAK LIMITED (GB) | 1993-04-14 | — | — | EP | disclosed |
| WO-1992015042-A1 | PHOTOGRAPHIC HIGH CONTRAST SILVER HALIDE MATERIALS | KODAK LIMITED (GB) | 1992-09-03 | — | — | WO | disclosed |
| EP-0267264-B1 | HIGH CONTRAST DEVELOPMENT OF PHOTOGRAPHIC ELEMENTS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1990-07-25 | — | — | EP | disclosed |