Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6872143 | 1.00 | ALDH1A1 (0.55) | ALDH1A1KDM4ERAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6877624 | 0.90 | GAA (0.51) | ALDH1A1KDM4ERAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6877615 | 0.90 | GAA (0.51) | ALDH1A1KDM4ERAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6460402 | 0.90 | MCHR1 (0.44) | ALDH1A1KDM4ERAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6460410 | 0.90 | MCHR1 (0.44) | ALDH1A1KDM4ERAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6873339 | 0.89 | ALDH1A1 (0.58) | ALDH1A1KDM4ERAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6873332 | 0.89 | ALDH1A1 (0.58) | ALDH1A1KDM4ERAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6879533 | 0.89 | MCHR1 (0.43) | ALDH1A1KDM4ERAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6879529 | 0.89 | MCHR1 (0.43) | ALDH1A1KDM4ERAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6460357 | 0.88 | EPHX1 (0.55) | ALDH1A1KDM4ERAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |