Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.42 |
| ▸ | F7 | P08709 | 18/20 | 0.38 |
| ▸ | F2 | P00734 | 10/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 10/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 10/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6874667 | 0.91 | F10 (0.40) | F10F7F2PRSS1PRSS2 | |
| SCHEMBL6874415 | 0.88 | F10 (0.52) | F10F7F2PRSS1PRSS2 | |
| Acetic Acid SCHEMBL6875565 | 0.85 | F10 (0.57) | F10F7F2PRSS1PRSS2 | |
| SCHEMBL7149887 | 0.85 | F10 (0.43) | F10F7PRSS1PRSS2PRSS3 | |
| SCHEMBL6871330 | 0.83 | F10 (0.40) | F10F7F2PRSS1PRSS2 | |
| SCHEMBL6874216 | 0.82 | F10 (0.48) | F10ACACB | |
| SCHEMBL6874220 | 0.82 | F10 (0.48) | F10ACACB | |
| SCHEMBL7144475 | 0.81 | F10 (0.42) | F10F7F2PRSS1PRSS2 | |
| SCHEMBL7153753 | 0.81 | L3MBTL1 (0.44) | F10F7 | |
| SCHEMBL7153757 | 0.81 | L3MBTL1 (0.44) | F10F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474391-A1 | WATER SOLUBLE PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003066588-A1 | WATER SOLUBLE PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-08-14 | — | — | WO | disclosed |