Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 9/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6872194 | 1.00 | KMT2A (0.49) | KMT2AMCHR1ADRA2AADRA1AHTR2B | |
| SCHEMBL6458189 | 0.89 | SMN1; SMN2 (0.55) | KMT2AMCHR1ADRA2AADRA1AHTR2B | |
| SCHEMBL6458182 | 0.89 | SMN1; SMN2 (0.55) | KMT2AMCHR1ADRA2AADRA1AHTR2B | |
| SCHEMBL6878427 | 0.87 | MCHR1 (0.46) | KMT2AMCHR1ADRA2AADRA1AHTR2B | |
| SCHEMBL6878431 | 0.87 | MCHR1 (0.46) | KMT2AMCHR1ADRA2AADRA1AHTR2B | |
| SCHEMBL6873487 | 0.86 | MCHR1 (0.49) | MCHR1ADRA2AADRA1AHTR2BHRH1 | |
| SCHEMBL6873490 | 0.86 | MCHR1 (0.49) | MCHR1ADRA2AADRA1AHTR2BHRH1 | |
| SCHEMBL13793247 | 0.84 | MCHR1 (0.56) | MCHR1ADRA2AADRA1AHTR2BHRH1 | |
| SCHEMBL6880466 | 0.82 | MCHR1 (0.46) | MCHR1ADRA2AADRA1AHTR2BHRH1 | |
| SCHEMBL6880462 | 0.82 | MCHR1 (0.46) | MCHR1ADRA2AADRA1AHTR2BHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |