Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A2 | O00482 | 1/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28530376 | 0.86 | NR5A2 (0.36) | NR5A2NR5A1PTGS1PTGS2GAA | |
| SCHEMBL29487596 | 0.83 | ALDH1A1 (0.35) | NR5A2NR5A1GAAHTTALDH1A1 | |
| SCHEMBL38993 | 0.83 | ALDH1A1 (0.35) | NR5A2NR5A1GAAHTTALDH1A1 | |
| SCHEMBL3623376 | 0.81 | ALDH1A1 (0.33) | NR5A2NR5A1GAAHTTALDH1A1 | |
| SCHEMBL27848273 | 0.80 | ALDH1A1 (0.33) | NR5A2NR5A1GAAHTTALDH1A1 | |
| SCHEMBL193901 | 0.79 | GAA (0.36) | PTGS1PTGS2GAAHTTALDH1A1 | |
| SCHEMBL6872532 | 0.77 | NR5A2 (0.37) | NR5A2NR5A1GAAHTTALDH1A1 | |
| SCHEMBL3632901 | 0.77 | GAA (0.34) | GAAHTTALDH1A1MAPK1NPSR1 | |
| SCHEMBL16305038 | 0.75 | GAA (0.33) | GAAHTTPKM | |
| SCHEMBL9231435 | 0.73 | GAA (0.32) | PTGS1PTGS2GAAHTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6809208-B2 | OXIDATION, HEAT AND LIGHT RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-10-26 | — | — | US | disclosed |
| US-6610765-B1 | Excellent stability against oxidative, thermal or light degradation; polymeric dispersing or solvating agent having amphiphilic properties; polyacrylates, polysiloxanes, polyvinyl acetate or block copolymers | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-08-26 | — | — | US | disclosed |