Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CDK9 | P50750 | 1/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1903330 | 1.00 | HSD17B10 (0.62) | HSD17B10MAPK1EPHX2SMN1; SMN2TP53 | |
| SCHEMBL15971313 | 0.85 | HSD17B10 (0.66) | HSD17B10MAPK1EPHX2SMN1; SMN2TP53 | |
| SCHEMBL6374964 | 0.85 | HSD17B10 (0.66) | HSD17B10MAPK1EPHX2SMN1; SMN2TP53 | |
| SCHEMBL9056827 | 0.85 | HSD17B10 (0.66) | HSD17B10MAPK1EPHX2SMN1; SMN2TP53 | |
| SCHEMBL29687180 | 0.84 | KIF11 (0.51) | MAPK1TP53TSHRNPC1RAB9A | |
| SCHEMBL20334992 | 0.84 | MAPK1 (0.78) | HSD17B10MAPK1EPHX2SMN1; SMN2TP53 | |
| SCHEMBL20334993 | 0.84 | MAPK1 (0.78) | HSD17B10MAPK1EPHX2SMN1; SMN2TP53 | |
| SCHEMBL29687222 | 0.84 | KIF11 (0.51) | MAPK1TP53TSHRNPC1RAB9A | |
| SCHEMBL29687159 | 0.83 | MDM2 (0.58) | MAPK1SMN1; SMN2TP53TSHRCLK4 | |
| SCHEMBL29687046 | 0.83 | KIF11 (0.58) | MAPK1EPHX2SMN1; SMN2TP53EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452522-A2 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2004-09-01 | — | — | EP | disclosed |