Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10088515 | 0.82 | NOTUM (0.44) | ALDH1A1MAPTNOTUMSMN1; SMN2LMNA | |
| SCHEMBL6018650 | 0.72 | ALDH1A1 (0.38) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL10493450 | 0.68 | IKBKB (0.43) | ALDH1A1MAPTNOTUMSMN1; SMN2LMNA | |
| SCHEMBL9782634 | 0.65 | NPC1 (0.46) | ALDH1A1MAPTLMNAKMT2APOLB | |
| SCHEMBL19297878 | 0.63 | PSEN1 (0.35) | MAPTLMNAKMT2AMEN1KDM4E | |
| SCHEMBL14089362 | 0.61 | SUCNR1 (0.40) | ALDH1A1MAPTSMN1; SMN2KMT2APTGDR2 | |
| SCHEMBL16273861 | 0.61 | CYP3A4 (0.41) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL7856358 | 0.61 | MAPK14 (0.40) | ALDH1A1MAPTRAB9AKDM4ECYP1A2 | |
| Trifluoroacetic Acid SCHEMBL10489622 | 0.61 | IKBKB (0.43) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL24839055 | 0.60 | MAPT (0.43) | CASP3SENP8SENP7SENP6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412347-A1 | PROCESS FOR THE PREPARATION OF HETEROCYCLIC PENTALENE DERIVATIVES | Basell Polyolefine GmbH (DE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003014107-A1 | PROCESS FOR THE PREPARATION OF HETEROCYCLIC PENTALENE DERIVATIVES | BASELL POLYOLEFINE GMBH (DE) | 2003-02-20 | — | — | WO | disclosed |