Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6873249 | 1.00 | MCHR1 (0.45) | MCHR1ADRA2AMAPK1CTSSCTSK | |
| SCHEMBL6875338 | 0.88 | CTSS (0.43) | MCHR1ADRA2ACTSSCTSKNPY5R | |
| SCHEMBL6875332 | 0.88 | CTSS (0.43) | MCHR1ADRA2ACTSSCTSKNPY5R | |
| SCHEMBL6876580 | 0.87 | MCHR1 (0.43) | MCHR1ADRA2AMAPK1NPY5RADRA1A | |
| SCHEMBL6871904 | 0.87 | MCHR1 (0.47) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6871900 | 0.87 | MCHR1 (0.47) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6876575 | 0.87 | MCHR1 (0.43) | MCHR1ADRA2AMAPK1NPY5RADRA1A | |
| SCHEMBL6874578 | 0.84 | MCHR1 (0.57) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL13793567 | 0.83 | MCHR1 (0.65) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6874661 | 0.83 | MCHR1 (0.44) | MCHR1ADRA2ACTSSCTSKNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |