⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21694344 | 0.79 | — | — | |
| SCHEMBL20444744 | 0.79 | — | — | |
| SCHEMBL5555811 | 0.79 | — | — | |
| SCHEMBL22798495 | 0.72 | — | — | |
| SCHEMBL22797631 | 0.72 | — | — | |
| SCHEMBL22707383 | 0.70 | — | — | |
| SCHEMBL22707370 | 0.70 | — | — | |
| SCHEMBL21122594 | 0.70 | — | — | |
| SCHEMBL24673045 | 0.70 | — | — | |
| SCHEMBL22797567 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831069-B2 | Having substituents at the C4' and C5' positions of the ribofuranose moiety; anticancer and immunomodulating effects at reduced cytotoxicity; treating autoimmune diseases, cancer, dermatitis | RIBAPHARM INC. | 2004-12-14 | — | — | US | disclosed |
| EP-1212326-A4 | PYRROLO 2,3-d]PYRIMIDINE NUCLEOSIDE ANALOGS | ICN PHARMACEUTICALS (US) | 2003-08-20 | — | — | EP | disclosed |
| EP-1212326-A1 | PYRROLO 2,3-d]PYRIMIDINE NUCLEOSIDE ANALOGS | ICN Pharmaceuticals, Inc. (US) | 2002-06-12 | — | — | EP | disclosed |
| US-20020035077-A1 | Pyrrolo[2,3-d]pyrimidine nucleoside analogs | CEQUENT PHARMACEUTICALS, INC. | 2002-03-21 | — | — | US | disclosed |
| WO-2001027114-A1 | PYRROLO[2,3-d]PYRIMIDINE NUCLEOSIDE ANALOGS | ICN PHARMACEUTICALS, INC. (US) | 2001-04-19 | — | — | WO | disclosed |