⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20444744 | 1.00 | — | — | |
| SCHEMBL15489116 | 0.83 | — | — | |
| SCHEMBL21694344 | 0.82 | — | — | |
| SCHEMBL6873309 | 0.79 | — | — | |
| SCHEMBL5551824 | 0.76 | ALDH1A1 (0.47) | — | |
| SCHEMBL12449344 | 0.76 | GLB1 (0.33) | — | |
| SCHEMBL1716374 | 0.74 | SMYD2 (0.32) | — | |
| SCHEMBL24673045 | 0.72 | — | — | |
| SCHEMBL22797631 | 0.70 | — | — | |
| SCHEMBL22798495 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060504-A1 | 2' and 3'-nucleoside prodrugs for treating Flaviviridae infections | IDENIX PHARMACEUTICALS, INC. | 2007-03-15 | — | — | US | disclosed |
| US-20070060541-A1 | 2' and 3'-nucleoside prodrugs for treating Flaviviridae infections | IDENIX PHARMACEUTICALS, INC. | 2007-03-15 | — | — | US | disclosed |
| US-20070060505-A1 | 2' and 3'-nucleoside prodrugs for treating Flaviviridae infections | IDENIX PHARMACEUTICALS, INC. | 2007-03-15 | — | — | US | disclosed |
| US-20070060498-A1 | 2' and 3'-nucleoside prodrugs for treating Flaviviridae infections | IDENIX (CAYMAN) LIMITED (KY) | 2007-03-15 | — | — | US | disclosed |
| US-20070060503-A1 | 2' and 3'-nucleoside prodrugs for treating Flaviviridae infections | IDENIX PHARMACEUTICALS, INC. | 2007-03-15 | — | — | US | disclosed |
| US-20070042990-A1 | 2' and 3'-nucleoside prodrugs for treating Flaviviridae infections | IDENIX PHARMACEUTICALS, INC. | 2007-02-22 | — | — | US | disclosed |
| US-20070037735-A1 | 2' and 3'-nucleoside prodrugs for treating Flaviviridae infections | IDENIX PHARMACEUTICALS, INC. | 2007-02-15 | — | — | US | disclosed |
| US-7138376-B2 | Methods and compositions for treating hepatitis C virus using 4'-modified nucleosides | IDENIX PHARMACEUTICALS, INC. (US) | 2006-11-21 | — | — | US | disclosed |
| US-7081449-B2 | Pyrido[2,3-d]pyrimidine and pyrimido[4,5-d]pyrimidine nucleosides | VALEANT RESEARCH & DEVELOPMENT (US) | 2006-07-25 | — | — | US | disclosed |
| US-6831069-B2 | Having substituents at the C4' and C5' positions of the ribofuranose moiety; anticancer and immunomodulating effects at reduced cytotoxicity; treating autoimmune diseases, cancer, dermatitis | RIBAPHARM INC. | 2004-12-14 | — | — | US | disclosed |
| US-20040006007-A1 | Methods and compositions for treating hepatitis C virus using 4'-modified nucleosides | IDENIX PHARMACEUTICALS, INC. | 2004-01-08 | — | — | US | disclosed |
| US-20040006002-A1 | Methods and compositions for treating flaviviruses and pestiviruses using 4'-modified nucleoside | SOMMADOSSI JEAN-PIERRE (US) | 2004-01-08 | — | — | US | disclosed |
| EP-1212326-A4 | PYRROLO 2,3-d]PYRIMIDINE NUCLEOSIDE ANALOGS | ICN PHARMACEUTICALS (US) | 2003-08-20 | — | — | EP | disclosed |
| US-20030144502-A1 | Pyrido[2,3-d]pyrimidine and pyrimido[4,5-d]pyrimidine nucleosides | MDRNA RESEARCH, INC. | 2003-07-31 | — | — | US | disclosed |
| EP-1303282-A1 | PYRIDO[2,3-D]PYRIMIDINE AND PYRIMIDO[4,5-D]PYRIMIDINE NUCLEOSIDES | Ribapharm, Inc. (US) | 2003-04-23 | — | — | EP | disclosed |
| CN-1384834-A | Pyrrolo [2,3-d] pyrimidine nucleoside analoys | ICN PHARMACEUTICALS (US) | 2002-12-11 | — | — | CN | disclosed |
| EP-1212326-A1 | PYRROLO 2,3-d]PYRIMIDINE NUCLEOSIDE ANALOGS | ICN Pharmaceuticals, Inc. (US) | 2002-06-12 | — | — | EP | disclosed |
| US-20020035077-A1 | Pyrrolo[2,3-d]pyrimidine nucleoside analogs | CEQUENT PHARMACEUTICALS, INC. | 2002-03-21 | — | — | US | disclosed |
| WO-2002003997-A1 | PYRIDO[2,3-D]PYRIMIDINE AND PYRIMIDO[4,5-D]PYRIMIDINE NUCLEOSIDES | RIBAPHARM INC. (US) | 2002-01-17 | — | — | WO | disclosed |
| WO-2001027114-A1 | PYRROLO[2,3-d]PYRIMIDINE NUCLEOSIDE ANALOGS | ICN PHARMACEUTICALS, INC. (US) | 2001-04-19 | — | — | WO | disclosed |