Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555728 | 0.94 | DHFR (0.49) | DHFR | |
| SCHEMBL6555433 | 0.92 | DHFR (0.52) | DHFR | |
| SCHEMBL6557272 | 0.92 | DHFR (0.48) | DHFR | |
| SCHEMBL6555237 | 0.92 | DHFR (0.48) | DHFR | |
| SCHEMBL6556693 | 0.91 | DHFR (0.61) | DHFR | |
| SCHEMBL6556667 | 0.90 | DHFR (0.49) | DHFR | |
| SCHEMBL6866235 | 0.90 | DHFR (0.49) | DHFR | |
| SCHEMBL6872100 | 0.89 | DHFR (0.48) | DHFR | |
| SCHEMBL6871589 | 0.88 | DHFR (0.48) | DHFR | |
| SCHEMBL6556200 | 0.88 | DHFR (0.48) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6821980-B1 | Substituted 5-benzyl-2,4-diaminopyrimidines | BASILEA PHARMACEUTICA AG (CH) | 2004-11-23 | — | — | US | disclosed |