Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 8/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.49 |
| ▸ | GRK6 | P43250 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6874670 | 1.00 | NPY5R (0.49) | NPY5RMCHR1ADRA2AGRK6APP | |
| SCHEMBL6873607 | 0.93 | NPY5R (0.45) | NPY5RMCHR1ADRA2AAPPBCHE | |
| SCHEMBL6873598 | 0.93 | NPY5R (0.45) | NPY5RMCHR1ADRA2AAPPBCHE | |
| SCHEMBL6873090 | 0.90 | MCHR1 (0.47) | NPY5RMCHR1ADRA2AAPPBCHE | |
| SCHEMBL6873084 | 0.90 | MCHR1 (0.47) | NPY5RMCHR1ADRA2AAPPBCHE | |
| SCHEMBL6874814 | 0.89 | MCHR1 (0.49) | NPY5RMCHR1ADRA2AAPPBCHE | |
| SCHEMBL6462424 | 0.89 | MCHR1 (0.49) | NPY5RMCHR1ADRA2AAPPBCHE | |
| SCHEMBL6874117 | 0.88 | MCHR1 (0.45) | NPY5RMCHR1ADRA2ATYRO3LMNA | |
| SCHEMBL6874121 | 0.88 | MCHR1 (0.45) | NPY5RMCHR1ADRA2ATYRO3LMNA | |
| SCHEMBL6875587 | 0.87 | MCHR1 (0.49) | NPY5RMCHR1ADRA2AAPPBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |