Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6871542 | 0.92 | ADORA2A (0.66) | ADORA2A | |
| SCHEMBL6871871 | 0.86 | ADORA2A (0.73) | ADORA2A | |
| SCHEMBL6870109 | 0.86 | ADORA2A (0.72) | ADORA2A | |
| SCHEMBL6869176 | 0.85 | ADORA2A (0.73) | ADORA2A | |
| SCHEMBL6873620 | 0.85 | ADORA2A (0.65) | ADORA2A | |
| SCHEMBL6867721 | 0.82 | ADORA2A (0.64) | ADORA2A | |
| SCHEMBL6871719 | 0.82 | ADORA2A (0.66) | ADORA2A | |
| SCHEMBL6872134 | 0.82 | ADORA2A (0.63) | ADORA2A | |
| SCHEMBL6869503 | 0.82 | ADORA2A (0.65) | ADORA2A | |
| SCHEMBL6871932 | 0.81 | ADORA2A (0.65) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | claimed |