Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 8/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 4/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.40 |
| ▸ | HRH1 | P35367 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6874132 | 1.00 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RCXCR4HTR2B | |
| SCHEMBL6869130 | 0.91 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RHTR2BADRA1A | |
| SCHEMBL6869135 | 0.91 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RHTR2BADRA1A | |
| SCHEMBL6874651 | 0.89 | MCHR1 (0.44) | MCHR1ADRA2ANPY5RHTR2BADRA1A | |
| SCHEMBL6874661 | 0.89 | MCHR1 (0.44) | MCHR1ADRA2ANPY5RHTR2BADRA1A | |
| SCHEMBL6878940 | 0.87 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RHTR2BADRA1A | |
| SCHEMBL6457942 | 0.87 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RHTR2BADRA1A | |
| SCHEMBL6463203 | 0.86 | MCHR1 (0.49) | MCHR1ADRA2ANPY5RHTR2BADRA1A | |
| SCHEMBL6876819 | 0.86 | MCHR1 (0.49) | MCHR1ADRA2ANPY5RHTR2BADRA1A | |
| SCHEMBL6876551 | 0.86 | ALDH1A1 (0.46) | MCHR1ADRA2ANPY5RCXCR4HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |