Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 7/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6874171 | 1.00 | MCHR1 (0.51) | MCHR1KDM4ELMNASMN1; SMN2APP | |
| SCHEMBL6875330 | 0.89 | MCHR1 (0.46) | MCHR1KDM4ELMNASMN1; SMN2APP | |
| SCHEMBL6875335 | 0.89 | MCHR1 (0.46) | MCHR1KDM4ELMNASMN1; SMN2APP | |
| SCHEMBL6877202 | 0.84 | MCHR1 (0.49) | MCHR1KDM4ELMNASMN1; SMN2APP | |
| SCHEMBL6878682 | 0.84 | MCHR1 (0.49) | MCHR1KDM4ELMNASMN1; SMN2APP | |
| SCHEMBL6877209 | 0.84 | MCHR1 (0.49) | MCHR1KDM4ELMNASMN1; SMN2APP | |
| SCHEMBL6878676 | 0.84 | MCHR1 (0.49) | MCHR1KDM4ELMNASMN1; SMN2APP | |
| SCHEMBL6464209 | 0.81 | MCHR1 (0.62) | MCHR1ADRA2ANPY5R | |
| SCHEMBL6877613 | 0.81 | MCHR1 (0.48) | MCHR1KDM4ELMNASMN1; SMN2ADRA2A | |
| SCHEMBL6877619 | 0.81 | MCHR1 (0.48) | MCHR1KDM4ELMNASMN1; SMN2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |