Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6876734 | 0.91 | MEN1 (0.51) | ALDH1A1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL6876725 | 0.91 | MEN1 (0.51) | ALDH1A1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL6460801 | 0.90 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL6458568 | 0.90 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL6463609 | 0.87 | MCHR1 (0.42) | ALDH1A1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL6463604 | 0.87 | MCHR1 (0.42) | ALDH1A1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL6867611 | 0.86 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL6867605 | 0.86 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL6873332 | 0.86 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MEN1KMT2AMCHR1 | |
| SCHEMBL6873339 | 0.86 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MEN1KMT2AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |