Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 7/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6874439 | 1.00 | MCHR1 (0.42) | MCHR1ADRA2ANPY5RMAPK14ADRA1A | |
| SCHEMBL6459327 | 0.92 | MCHR1 (0.37) | MCHR1ADRA2ANPY5RMAPK14ADRA1A | |
| SCHEMBL6880134 | 0.92 | MCHR1 (0.37) | MCHR1ADRA2ANPY5RMAPK14ADRA1A | |
| SCHEMBL13793380 | 0.87 | MCHR1 (0.55) | MCHR1ADRA2ANPY5RADRA1AHRH1 | |
| SCHEMBL13795362 | 0.82 | MCHR1 (0.52) | MCHR1ADRA2ANPY5RADRA1AHRH1 | |
| SCHEMBL6869135 | 0.81 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RADRA1AHRH1 | |
| SCHEMBL6869130 | 0.81 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RADRA1AHRH1 | |
| SCHEMBL6874138 | 0.80 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RADRA1AHRH1 | |
| SCHEMBL6874132 | 0.80 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RADRA1AHRH1 | |
| SCHEMBL6455286 | 0.79 | NPY5R (0.33) | MCHR1ADRA2ANPY5RMAPK14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |