Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6874434 | 1.00 | EGFR (0.47) | EGFRALDH1A1MAPTSMN1; SMN2ALOX12 | |
| SCHEMBL6874955 | 0.95 | EGFR (0.54) | EGFRALDH1A1MAPTSMN1; SMN2ALOX12 | |
| SCHEMBL6874938 | 0.95 | EGFR (0.54) | EGFRALDH1A1MAPTSMN1; SMN2ALOX12 | |
| SCHEMBL6874686 | 0.90 | RAB9A (0.53) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL6874693 | 0.90 | RAB9A (0.53) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL6868482 | 0.88 | SMN1; SMN2 (0.51) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL6868487 | 0.88 | SMN1; SMN2 (0.51) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL6867611 | 0.84 | SMN1; SMN2 (0.47) | ALDH1A1MAPTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL6867605 | 0.84 | SMN1; SMN2 (0.47) | ALDH1A1MAPTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL6878955 | 0.84 | MCHR1 (0.43) | ALDH1A1MAPTSMN1; SMN2ALOX12LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |