SCHEMBL6874674

SCHEMBL6874674

CCCC[C@H](N)CC(C)=O

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.43
CA1 P00915 2/20 0.43
ALDH1A1 P00352 2/20 0.42
SLC1A3 P43003 1/20 0.42
SLC1A2 P43004 1/20 0.42
SLC1A1 P43005 1/20 0.42
S1PR2 O95136 6/20 0.41
S1PR1 P21453 6/20 0.41
S1PR3 Q99500 5/20 0.41
S1PR4 O95977 4/20 0.41
DPP7 Q9UHL4 2/20 0.41
SLC15A1 P46059 1/20 0.41
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
DPP4 P27487 1/20 0.38
DPP8 Q6V1X1 1/20 0.38
DPP9 Q86TI2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25754164 1.00 CA2 (0.43) CA2CA1ALDH1A1SLC1A3SLC1A2
SCHEMBL28305103 0.91 S1PR2 (0.52) ALDH1A1S1PR2S1PR1S1PR3S1PR4
SCHEMBL13675239 0.91 S1PR2 (0.52) ALDH1A1S1PR2S1PR1S1PR3S1PR4
SCHEMBL1561204 0.91 S1PR2 (0.52) ALDH1A1S1PR2S1PR1S1PR3S1PR4
SCHEMBL638285 0.86
SCHEMBL7860013 0.82 CA2 (0.48) CA2CA1ALDH1A1SLC1A3SLC1A2
SCHEMBL288356 0.82 S1PR2 (0.57) CA2CA1ALDH1A1SLC1A3SLC1A2
SCHEMBL6807748 0.82 CA2 (0.48) CA2CA1ALDH1A1SLC1A3SLC1A2
SCHEMBL6466558 0.82 S1PR2 (0.57) CA2CA1ALDH1A1SLC1A3SLC1A2
SCHEMBL5496400 0.82 S1PR2 (0.57) CA2CA1ALDH1A1SLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011014494-A1 ENANTIO- AND STEREO-SPECIFIC SYNTHESES OF β-AMINO-α- HYDROXY AMIDES SCHERING CORPORATION (US) 2011-02-03 WO disclosed