Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ILK | Q13418 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL680380 | 0.84 | ILK (1.00) | ILK | |
| SCHEMBL686424 | 0.78 | ILK (0.63) | ILK | |
| SCHEMBL686412 | 0.73 | ILK (0.80) | ILK | |
| SCHEMBL5216183 | 0.69 | ILK (0.52) | ILK | |
| SCHEMBL687009 | 0.69 | ILK (1.00) | ILK | |
| SCHEMBL686402 | 0.67 | ILK (1.00) | ILK | |
| SCHEMBL686406 | 0.67 | ILK (1.00) | ILK | |
| SCHEMBL686387 | 0.66 | ILK (1.00) | ILK | |
| SCHEMBL13806286 | 0.66 | APP (0.63) | ILK | |
| SCHEMBL686438 | 0.66 | ILK (1.00) | ILK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542997-B1 | PYRAZOLYLBENZOTHIAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | DERMIRA CANADA INC (CA) | 2012-02-29 | — | — | EP | disclosed |